Search results for "Inosinic acid"

Uptake and Metabolism of Purine Nucleosides and Purine Nucleoside Analogues by Cells

1979

Since the discovery of purine nucleotides and purine nucleosides, 1847 by Liebig (1) (inosinic acid) and 1885 by Schulze et al. (2) (guanosine),it was only relatively recently that purine- and purine-nucleoside analogues have been considered to be effective antitumor or antiviral agents. It is due to Prusoff, Schabel and S.S. Cohen that on the other hand pyrimidine nucleoside analogues have already been used clinically as drugs for a number of years.